This cross-sectional study examined the associations among functional capacity, ejection fraction, and health-related quality of life (HRQoL) in stable heart failure patients. Twenty-one stable NYHA Class II and III heart failure patients (mean age = 56.9 ± 11.1 yrs; BMI = 28.9 ± 4.2 kg·m -2) participated in this study. The subjects underwent cardiopulmonary treadmill testing to determine peak oxygen consumption (VO2 peak = 16.9 ± 5.3 mL·kg-1 ·min-1) and ventilatory threshold (961.9 ± 308.4 ml). The Kansas City Cardiomyopathy Questionnaire (KCCQ) was used to assess HRQoL. Ejection fraction was assessed by echocardiogram (EF = 28.9 ± 8.03%). HRQoL was non-significantly (P>0.05) related to VO2 peak (r = 0.221), EF (r = 0.204), and ventilatory threshold (r = 0.108). However, the physical limitation domain of the KCCQ was independently related (P<0.05) to VO2 peak (r = 0.621) and ventilatory threshold (r = 0.555). The physiological markers of cardiovascular health were specifically related to the physical limitations domain of the KCCQ. These same markers, however, were not associated with overall HRQoL, which suggest that both quantitative and qualitative measures may be used to better assess cardiovascular health in heart failure patients.
|Journal||Journal of Exercise Physiology Online|
|Publication status||Published - 2012|